If you are in Colombia there are many flights from the main cities such as Bogotá, Cali, Medellín, Cartagena, or Barranquilla. The airlines with the most routes are Latam Colombia, Wingo, and Viva Colombia.
These last two are low-cost airlines that, although prices vary greatly depending on the season, can find tickets for 142,000 Colombian pesos (50 dollars) but keep in mind the weight of luggage.
If you are outside of Colombia, you can get from Panama to San Andrés Island directly, the only airline that takes you is Copa Airlines but the flight can cost more than 1,500,000 Colombian pesos, that is, more than 500 dollars, the best option is to first arrive in a main city in Colombia, preferably Bogotá.
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